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Why DUPIXENT?

A Unique Treatment Approach

Whether you’re a patient or a caregiver of someone with EoE, we understand what you’re going through. DUPIXENT targets an underlying cause of EoE to help control symptoms.

FDA-approved

DUPIXENT is the first and only FDA-approved treatment of its kind for EoE in patients as young as 1 year old, weighing at least 33 lb.

Reduces inflammation

DUPIXENT targets a source of inflammation that can lead to EoE. It is not a steroid or immunosuppressant.

Proven results

In clinical trials, DUPIXENT reduced inflammation in the esophagus in both adults and children as young as 1 year old, weighing at least 33 lb.*

Demonstrated safety

DUPIXENT has a demonstrated safety profile in both adults and children as young as 1 year old, weighing at least 33 lb.*

*Based on clinical trials with 240 adult and pediatric patients (12+ years of age, weighing at least 88 lb) with EoE at Week 24 and results from 61 patients ages 1-11 years old (≥33 lb) with EoE.

The most common side effects in patients with eosinophilic esophagitis include: injection site reactions, upper respiratory tract infections, cold sores in your mouth or on your lips, and joint pain (arthralgia).

1 Dose Given Weekly or Every Other Week†

†Depending on patient’s
weight (ages 1 year and older,
weighing at least 33 lb).

A Look Inside: How DUPIXENT Works for EoE

Learn how DUPIXENT works to target an underlying inflammation that can contribute to EoE.

For more on life with DUPIXENT, explore
recommended dosing and administration options.

DUPIXENT Dosing for EoE  

Results in Adults AND ADOLESCENTS at 24 Weeks

Based on a clinical trial with 240 adult and pediatric patients (12+ years weighing at least 88 lb) with EoE at Week 24:

DUPIXENT was proven to

IMPROVE SWALLOWING

DUPIXENT

reduced INFLAMMATION
IN THE ESOPHAGUS

The most common side
effects include:

  • Injection site reactions
  • Upper respiratory tract infections
  • Cold sores in your mouth or on your lips
  • Joint pain (arthralgia)

View the possible side effects of DUPIXENT in patients with eosinophilic esophagitis.

YOUR NEXT STEP BEFORE TALKING TO YOUR DOCTOR

Watch a real patient, caregivers, and a gastroenterologist discuss
how to have productive conversations about EoE with a doctor.

After, fill out your personalized doctor discussion guide to help your doctor determine if
DUPIXENT is right for you.

WATCH THE VIDEO NOW

Results in Children

Based on a clinical trial with 61 patients (ages 1 to 11 years weighing at least 33 lb) with EoE in a 2-part study:

DUPIXENT

reduced INFLAMMATION
IN THE ESOPHAGUS

Caregivers observed that children

experienced FEWER DAYS WITH
EoE SIGNS AND SYMPTOMS

as early as 4 months and at 1 year†

VISIBLE IMPROVEMENTS
IN THE ESOPHAGUS

were seen in children

†As measured by the Pediatric Eosinophilic Esophagitis Sign/Symptom Questionnaire for Caregivers (PESQ-C).

The most common side
effects include:

  • Injection site reactions
  • Upper respiratory tract infections
  • Cold sores in your mouth or on your lips
  • Joint pain (arthralgia)

View the possible side effects of DUPIXENT in patients with eosinophilic esophagitis.

YOUR NEXT STEP BEFORE TALKING TO YOUR DOCTOR

Watch a real patient, caregivers, and a gastroenterologist discuss
how to have productive conversations about EoE with a doctor.

After, fill out your personalized doctor discussion guide to help your doctor determine if
DUPIXENT is right for you.

WATCH THE VIDEO NOW

Learn More With the Patient Brochure

Learn More With the Patient Brochure

For more on how DUPIXENT treats EoE, download the
patient brochure.

Download Brochure

Discover Your EoE Community

Your EoE journey may be unique, but you’re not alone. Explore our educational webinars to hear from others with EoE and how DUPIXENT helped them find relief from their symptoms.

Find a Webinar

Looking for More Personal
Guidance?

Connect with a DUPIXENT MyWay® Mentor to speak one-on-one with others who have been in your shoes.

Connect with
a Mentor

FREQUENTLY ASKED QUESTIONS

DUPIXENT is indicated for the treatment of adult and pediatric patients aged 1 year and older who weigh at least 33 lb (15 kg) with eosinophilic esophagitis (EoE).

Fill out our personalized doctor discussion guide to help guide your conversation with your doctor and discover whether DUPIXENT may be right for you.

DUPIXENT is a biologic. Biologics are specialty medicines made inside living cells and designed to target specific parts of the immune system involved in a particular disease. They are processed in the body differently than oral or topical medications. To be effective and work properly, most biologics are delivered by injection.

DUPIXENT targets an underlying source of inflammation, which contributes to EoE.

Before using DUPIXENT, tell your doctor about all your medical conditions, including if you:

  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or if you have EoE and asthma and use an asthma medicine. Do not change or stop your other medicines, including corticosteroid medicine or other asthma medicine, without talking to your healthcare provider. This may cause other symptoms that were controlled by those medicines to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms:
    • breathing problems or wheezing
    • swelling of the face, lips, mouth, tongue, or throat
    • fainting, dizziness, feeling lightheaded
    • fast pulse
    • fever
    • hives
    • joint pain
    • general ill feeling
    • itching
    • skin rash
    • swollen lymph nodes
    • nausea or vomiting
    • cramps in your stomach-area
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects of DUPIXENT in patients with eosinophilic esophagitis include: injection site reactions, upper respiratory tract infections, cold sores in your mouth or on your lips, and joint pain (arthralgia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

In May 2022, the U.S. Food and Drug Administration (FDA) approved DUPIXENT® to treat patients with EoE aged 12 years and older, weighing at least 40 kg. In January 2024, the FDA expanded DUPIXENT’s approval to treat patients with EoE aged 1 year and older, weighing at least 15 kg.