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DUPIXENT was studied in 3 clinical trials with more than 2,800 people 12 years of age and older with moderate-to-severe asthma.
In a study of people dependent
on oral corticosteroids.
The most common side effects include:
The risks of DUPIXENT were evaluated in 2 clinical studies involving 2,359 patients ages 12 and older. Common side effects are indicated in the table below. DUPIXENT was also studied in another study of steroid-dependent patients. Side effects in table are greater than placebo.
Most common side effects |
DUPIXENT 200 mg (779 patients) |
Placebo (792 patients) |
---|---|---|
Injection site reactiona |
14% | 6% |
Pain in the (oropharyngeal pain) |
throat2% | 1% |
High count of white blood cell (eosinophilia) |
a certain 2% | <1% |
View the possible side effects of DUPIXENT in patients with moderate-to-severe eosinophilic or oral corticosteroid–dependent asthma.
aInjection site reaction includes injection site reaction, pain, bruising, and swelling. Talk to your doctor about this side effect. If experienced, try a cold compress.
For both adults and children, the safety profile of DUPIXENT through Week 52 was generally consistent with the safety profile observed at Week 24.
When my doctor suggested DUPIXENT, I was open to it. We had a
candid conversation. I asked a lot of questions.
Rachel,
Real patient. Individual results may vary.
Not sure how to talk to your doctor about DUPIXENT? Our doctor
discussion guide can help guide the conversation.
Select the best option to receive information to address your specific needs.
Great! Consider discussing DUPIXENT as a treatment option with your specialist. Let us help you create a personalized doctor discussion guide to bring to your next appointment.
Working with an asthma specialist can help you or your loved one create a personalized treatment plan and discuss medicines like DUPIXENT.
It’s important to work with a specialist for thorough asthma management. Consider setting up an appointment with an allergist or pulmonologist.
Learn what happens once you’ve been prescribed treatment, the importance of staying on track
with your DUPIXENT treatment, and the role you and your doctor can play.
Starting DUPIXENT
Transcript
Did you know that each time your DUPIXENT® (dupilumab) is shipped to you, you’re getting more than just your medicine in that delivery box?
It’s true!
DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in adults and children 6 years of age and older whose asthma is not controlled with their current asthma medicines. DUPIXENT is not used to treat sudden breathing problems.
With each delivery of DUPIXENT, you’re also getting an opportunity for better control of your asthma.
Just imagine what that improvement could mean for you.
Each time you open that box, think about how DUPIXENT may help you do more of what you want in life.
What could you do with more freedom from asthma?
What could you spend more of your time doing?
And remember, if you take your DUPIXENT every other week as prescribed, you’re not only working to help prevent attacks, you’re also giving yourself the opportunity to do more with less asthma.
And don’t forget, DUPIXENT MyWay® Nurse Educators are just a phone call away.
TAKING DUPIXENT
Transcript
RACHEL: It's really important to me to take DUPIXENT as directed by my doctor. I make it a priority. My severe asthma is something I need to keep controlled. It's not going away. It's something I live with, and I need to manage it.
SHARRON: I understand that my severe asthma is a chronic condition, there will always be underlying inflammation, and that my severe asthma will never quit and neither can I.
RACHEL: I feel motivated to stay on my treatment schedule, because I know what it feels like not to be able to breathe well, and I want to do everything I can to help avoid being in that situation.
SHARRON: What motivates me to stay on treatment is knowing that my current treatment plan is working. With DUPIXENT I’m able to do more of what I want to do and with less asthma.
RACHEL: Having a routine has definitely helped me stay on track. I take my DUPIXENT every two weeks. It’s a system I’m comfortable with.
SHARRON: So, I have a DUPIXENT reminder on my calendar and an alarm set on my phone. It’s scheduled for every two weeks, and it’s like a ritual for me. It is how I take care of myself.
RACHEL: When I first started out on DUPIXENT, the DUPIXENT MyWay® patient support program was really helpful. They are there to help you answer questions about DUPIXENT. They can help you set up reminders to start and maintain a routine. But remember, your doctor is always the best source of information.
SHARRON: My doctor recommended that I reach out to DUPIXENT MyWay after he wrote the prescription. I’m so glad he did! They’ve been a tremendous resource for me, and it’s good to know that I can reach out to them.
SHARRON: Before I started DUPIXENT, I told my doctor about all the medical conditions I had and medications I was taking.
RACHEL: My doctor and I talked about the potential benefits and risks of treatment, including the most common side effects such as injection site reactions, and some serious side effects including allergic reactions that can sometimes be severe, inflammation of your blood vessels, and joint aches and pain.
SHARRON: Over time, I’ve definitely gotten more used to taking DUPIXENT. It’s a part of my life, just like going to the doctor.
RACHEL: I am comfortable taking DUPIXENT every two weeks. I know that it helps control my asthma, and I feel that it's helping prevent me from another asthma attack. It’s what my doctor and I decided I need to do.
VO:
The average age of the patients in the study was 49 years old. These patients averaged 2 asthma attacks in the previous year, and 64% were on a high-dose inhaled corticosteroids.
In clinical trials, the impact of DUPIXENT on lung function was studied in patients 6 to 11 years of age and patients 12 years of age and older. Patients in each age group saw improved lung function in as little as 2 weeks.
Learn how DUPIXENT helped treat children 6 to 11 years old with their moderate-to-severe asthma.
DUPIXENT can cause serious side effects, including:
The most common side effects of DUPIXENT include:
Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.