For questions about financial assistance,
call 1-844-DUPIXENT, option 1 or
click to learn more
DUPIXENT IS NOW APPROVED
TO TREAT ALLERGIC FUNGAL
RHINOSINUSITIS (AFRS)
DUPIXENT is the only FDA-approved biologic treatment for
allergic fungal rhinosinusitis (AFRS) for adults and children
ages 6 years and up who have had surgery on their nose or
sinuses in the past.
Patient Portrayal
A DIFFERENCE YOU CAN FEEL
DUPIXENT was studied in a 52-week clinical trial in 62 adult and pediatric patients aged 6 years
and older with AFRS who have had surgery on their nose or sinuses in the past. During the study,
patients were allowed to continue background intranasal corticosteroids.
WITH DUPIXENT:
Patients achieved improved sinus imaging results compared to those on placebo at week 52 (50% reduction vs 10% reduction).
A lower score on sinus imaging testing could indicate reduced swelling or mucus
Patients saw a reduced need for sinus surgery and/or oral steroids by 92%, compared to placebo at week 52
Some patients saw improvements in as
early as one month.*
Patients experienced an 81% reduction in nasal congestion at week 52, compared to 11% on placebo
Some patients had an improved sense of smell in as little as 2 weeks†,‡
Patients saw their nasal polyps shrink by approximately 63% at week 52 compared to 4% on placebo
Don’t stop taking your corticosteroid medicine unless instructed by your doctor.
*Analysis at one month was not evaluated during the clinical trial, and any results at one month may be due to chance. Individual results may vary.
†Analysis at 2 weeks was not evaluated during the clinical trial, and any results at 2 weeks may be due to chance. Individual results may vary.
‡ As measured by a patient-reported scratch-and-sniff test that measures the ability to identify different smells.
THE MOST COMMON SIDE EFFECTS FOR AFRS INCLUDE:
- Injection site reactions
- Eye problems, including eye and eyelid inflammation,
redness, swelling, itching, eye infection, and blurred vision - High count of a certain white blood cell (eosinophilia)
- Stomach problems (gastritis)
- Joint pain (arthralgia)
- Trouble sleeping (insomnia)
- Toothache
DUPIXENT IS THE FIRST AND ONLY TREATMENT OF ITS KIND, DESIGNED TO
TARGET TWO OF THE KEY SOURCES OF INFLAMMATION IN AFRS
HOW DUPIXENT WORKS
DUPIXENT is not a steroid or
immunosuppressant
DUPIXENT is a prescription biologic medicine
given under the skin (subcutaneous
injection) that helps block two of the key
sources of inflammation in AFRS
DUPIXENT continuously works between
doses to help treat AFRS
Patient Portrayal
start a productive conversation with your doctor
Talk to your specialist if you:
- Have nasal polyps with thick mucus
- Feel like your nose is constantly blocked
- Experience a reduced sense of smell
Help prepare for a conversation with your specialist by filling out the personalized discussion guide to bring to your next appointment.
HOW TO TAKE DUPIXENT
Use DUPIXENT exactly as prescribed by your healthcare provider. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 6 to less than 12 years old, DUPIXENT should be given by a caregiver. In children 12 years and older, it is recommended that DUPIXENT be administered under the supervision of an adult.
Once prescribed, DUPIXENT is injected subcutaneously (under the skin) in accordance with the accompanying chart.
| BODY WEIGHT |
RECOMMENDED DOSAGE |
|
|---|---|---|
| ADULTS (18+ years): | Any weight | 300 mg every 2 weeks |
| CHILDREN AND TEENS (6-17 years): |
132 lb or more | 300 mg every 2 weeks |
| 66 to less than 132 lb | 200 mg every 2 weeks | |
| 33 to less than 66 lb | 300 mg every 4 weeks |
PRE-FILLED PEN
PRE-FILLED SYRINGE
help is available with DUPIXENT MyWay ®
DUPIXENT MyWay is a patient support program designed to help you throughout your treatment journey. Enroll in
DUPIXENT MyWay for access to:
DUPIXENT MyWay for access to:
INJECTION SUPPORT & TRAINING
One-on-one supplemental injection support and training with nurse
educators in person, virtually, or by phone
educators in person, virtually, or by phone
PRESCRIPTION SCHEDULING
Help coordinating deliveries of your prescription
TIPS, TOOLS,
& RESOURCES
Practical tips, tools, and resources designed to help you every step of the way
DUPIXENT is given as an injection under the skin (subcutaneous injection). You must be shown the right way by your
healthcare provider before injecting DUPIXENT.
Learn more by calling 1-844-387-4936, option 1
Monday-Friday, 8 am-9 pm ET
Monday-Friday, 8 am-9 pm ET
Patient Portrayal
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